New selective PAD4 inhibitors binding a calcium-deficient sort of the PAD4 enzyme have validated the important enzymatic position of human and mouse PAD4 in equally histone citrullination and neutrophil extracellular trap development for, to our know-how, The very first time. The therapeutic possible of PAD4 inhibitors can now be explored. https://horacej655vgr7.win-blog.com/profile