Atrial septal defect (ASD) is a congenital heart defect characterized by an opening in the atrial septum. About 1/3 of patients with Noonan syndrome caused by mutation in the PTPN11 gene have ASD. The prevalence of ASD is estimated at 100 per 100. 000 live births. https://www.alarecre.com/Virescent-Harmony-Galaxy-A14-5G-Clear-Case-p106336/