Environmental or self-antigens and homotypic interactions result in BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other signals from your microenvironment and growing the activation of anti-apoptotic and proliferation pathways.31,32 Genomic scientific studies have determined recurrent mutations in genes regulating tumor mobile-microenvironment int... https://ewartz864rzh0.wikiadvocate.com/user